■業績一覧
２００５年業績収集
ー原著論文ー
1.Yoshida M, Nakamura T, Sei A, Kikuchi T, Takagi K, Matsukawa A. Intervertebral disc cells produce tumor necrosis factor-a, interleukin-1b and monocyte chemoattractant protein-1 immediately after herniation
An experimental study using a new herniation model. Spine 30: 55-61, 2005.
2. Matsukawa A, Kurano R, Takemoto T, Kagayama M, Ito T.
Chief cell hyperplasia with structural and nuclear atypia: A variant of fundic gland polyp.
Path Res. Pract. 200; 817-821, 2005.
3.Matsukawa A, Kudo S, Maeda T, Numata K, Watanabe H, Takeda K, Akira S, Ito T. Stat3 in Resident Macrophages as a Repressor Protein of Inflammatory Response. J. Immunol. 175:3354-3359, 2005.
4.Kumai Y, Ito T, Matsukawa A, Yumoto E.
Effects of denervation on neuromuscular junctions in the thyroarytenoid muscle. Laryngoscope. 115:1869-1872, 2005.
5.Arima H, Motoyama K, Matsukawa A, Nishimoto Y, Hirayama F, Uekama K. Inhibitory effects of dimethylacetyl-beta-cyclodextrin on lipopolysaccharide-induced macrophage activation and endotoxin shock in mice.
Biochem Pharmacol. 70: 1506-1517, 2005.
6.Ogino T, Hosako M, Hiramatsu K, Omori M, Ozaki M, Okada S. Oxidative modification of IkB by monochloramine inhibits tumor necrosis factor a-induced NF-kB activation. Biochim. Biophys. Acta. 1746: 135-142, 2005.
7.Haga S, Ogawa W, Inoue H, Terui K, Ogino T, Igarashi R, Takeda K, Akira S, Enosawa S, Furukawa H, Todo S, Ozaki M.
Compensatory recovery of liver mass by Akt-mediated hepatocellular hypertrophy in liver-specific STAT3-deficient mice.
J. Hepatol. 43: 799-807, 2005.
8.Muranaka S, Fujita H, Fujiwara T, Ogino T, Sato EF, Akiyama J, Imada I, Inoue M, Utsumi K. Mechanism and Characteristics of Stimuli-Dependent ROS Generation in Undifferentiated HL-60 Cells. Antioxid Redox Signal. 7: 1367-1376, 2005.
9.Fujita H, Utsumi T, Muranaka S, Ogino T, Yano H, Akiyama J, Yasuda T, Utsumi K.
Involvement of Ras/extracellular signal-regulated kinase, but not Akt pathway in risedronate-induced apoptosis of U937 cells and its suppression by cytochalasin B. Biochem Pharmacol. 69: 1773-1784, 2005.
10. Otsuka F, Miyoshi T, Murakmi K, Inagaki K, Takeda M, Ujiki K, Ogura T, Omori M, Doihara H, Tanaka Y, Hashimoto K Makino H.
An extra-adrenal abdominal pheochromocytoma causing ectopic ACTH ssyndrome. Am. J.
hypertention 18: 1364-1368, 2005.
11. Okazaki Y, Iqbal M, Okada S.
Suppressive effects of dietary curcumin on the increased activity of renal ornithine decarboxylase in mice treated with a renal carcinogen, ferric nitrilotriacetate. Biochim.
Biophys. Acta 1740: 357-366, 2005.
12. 西本菜美、渡辺律子、大森昌子、豊田博：乳腺原発性悪性リンパ腫の一例 日本臨床細胞学会岡山支部会誌 24: 18-19 2005
13. 井上博文、藤田勝、松岡博美、今井みどり、森下由美子、中村聡子、市村浩一、大森昌子、柳井広之、吉野正：炎症性筋線維芽細胞性腫瘍の一例 日本臨床細胞学会岡山支部会誌 24: 24-25, 2005
14. 綾邦彦、野島郁子、長尾隆志、宮井貴之、高岩正典、井上勝、田中弘之、森島恒雄、飛田陽、徳丸久、小谷信行：シクロスポリン静注療法によって寛解しえたステロイド抵抗性ネフローゼ症候群の1例 日本小児科学会雑誌 109：543-544，2005
ー国際学会発表ー
1.Yoshimura T, Matsuyama W, Mizuta H, Matsukawa A.
Interferon-gamma and collagen synergistically induce monocyte chemoattractant protein-1 production in human polymorphonuclear leukocytes (PMN):
Role of discoidin domain receptor 1 (DDR1).
Experimental Biology 2005, April 2-6, 2005, San Diego, USA
２００４年業績
ー原著論文ー
1.Sukedai M, Tominaga K, Habu M, Matsukawa A, Nishihara T, Fukuda J. Involvement of tumor necrosis factor-a and interleukin-8 in antigen-induced arthritis of the rabbit temporomandibular joint. J. Oral Pathol.
Med. 33: 102-110, 2004.
2.Galligan C, Matsuyama W, Matsukawa A, Mizuta M, Hodge DR, Howard OMZ, Yoshimura T.
Up-regulated expression and activation of the orphan chemokine receptor, CCRL2, in rheumatoid arthritis. Arthritis Rheum.
50: 1806-1814, 2004.
3.Jiang Z, Berceli SA, Pfahnl CL, Wu L, Goldman DR, Tao M, Kagayama M, Matsukawa A, Ozaki CK.
Wall shear modulation of cytokines in the early vein graft.
J. Vasc. Surg. 40: 345-350, 2004.
4.Jakubzick C, Wen H, Matsukawa A, Keller M, Kunkel SL, Hogaboam CM.
Role of CCR4 ligands, CCL17 and CCL22, during Schistosoma mansoni egg-induced pulmonary granuloma formation in mice.
Am. J. Pathol. 165: 1211-1221, 2004.
5.Watanabe H, Numata K, Ito T, Takagi K, Matsukawa A.
Innate immune response in Th1- and Th2-dominant mouse strains.
Shock 22: 460-466, 2004.
6.LaFleur AM, Lukacs NW, Kunkel SL, Matsukawa A.
Role of CC Chemokine CCL6/C10 as a monocyte chemoattractant in a murine acute peritonitis.
Mediators Inflamm. 13: 349-355, 2004.
7.Hosako M, Ogino T, Omori M. Okada S.
Cell cycle arrest by monochloramine through the oxidation of retinoblastoma protein. Free Radical Biol.
Med. 36:112-122, 2004.
8.Iqbal M, Sharma SD, Okada S.
Probucol as a potent inhibitor of oxygen radical-induced lipid peroxidation and DNA damage: in vitro studies.
Redox Rep. 9: 167-172, 2004.
9.Hamazaki S, Fujisawa K, Okada S.
Intraneural perineurioma involving the ulnar nerve.
Pathol Int. 54: 371-375, 2004.
10. 大森昌子、岡崎泰昌、秋田みどり、井上博文、藤田勝、松岡博美、森下由美子、濱崎周次
膵solid pseudopapillary tumorの一例
日本臨床細胞学会岡山支部会誌 23: 37-38, 2004.
11. 松岡壮、西本菜美、渡辺律子、大森昌子、豊田博
男性乳腺腫瘍の二例
日本臨床細胞学会岡山支部会誌23: 29-30, 2004.
12. 橋本吉規、柳井広之、大森昌子、田口孝爾、松井俊浩、吉野正
Chordoid meningioma の１例
岡山外科病理雑誌 41: 1-5, 2004.
13. 中本周、岡崎泰昌、能登原憲司
脾原発の炎症性筋線維芽腫瘍の１例
岡山外科病理雑誌 39: 24-25, 2004.
14. 岡崎泰昌、Iqbal M、岡田茂
黒豆発酵クエン酸飲料の機能性—生体内での抗酸化機能評価鉄ニトリロ三酢酸（鉄-NTA）による酸化ストレスモデルでの検討—。
New Food Industry 46 : 6-10, 2004.
15. 森山友章、福田好世、谷口英人、三上肇、真鍋良二、波尾博志、本多啓介、大森昌子
低分化腺癌を主体にして亜有茎性隆起を形成した1型進行胃癌の1例 胃と腸
39: 827-832, 2004
ー国際学会発表ー
1.Galligan C, Matsuyama W, Matsukawa A, Mizuta M, Hodge DR, Howard OMZ, Yoshimura T. Up-regulated expression and activation of the orphan chemokine receptor, CCRL2, in rheumatoid arthritis. Experimental Biology 2004, April 17-21, 2004, Washington DC, USA
２００３年業績
ー原著論文ー
1.Rodriguez-Wilhelmi P, Montes R, Matsukawa A, Nariuchi H, Hurtado V, Montes M, Hermida J, Rocha E.
Tumor necrosis factor-a inhibition reduces CXCL-8 levels but fails to prevent fibrin generation and does not improve outcome in a rabbit model of endotoxic shock.
J. Lab. Clin. Med. 141: 257-264, 2003.
2.Asano-Kato N, Toda I, Shimmura S, Noda-Tsuruya T, Fukagawa K, Yoshinaga M, Matsukawa A, Tsubota K.
Detection of neutrophils and possible involvement of interleukin-8 in diffuse lamellar keratitis after laser in situ keratomileusis.
J. Cataract. Refract. Surg. 29: 1996-2000, 2003.
3.Matsukawa A, Takeda K, Kudo S, Maeda T, Kagayama M, Akira S.
Aberrant inflammation and lethality to septic peritonitis in mice lacking Stat3 in macrophages and neutrophils.
J. Immunol. 171: 6198-6205, 2003.
4.Than TA, Ogino T, Hosako M, Omori M, Tsuchiyama J, Okada S.
Physiological oxidants induce apoptosis and cell cycle arrest in a multidrug-resistant natural killer cell line,
NK-YS. Leukemia Lymphoma 44:2109-2116, 2000.
5.Haga S, Terui K, Zhang HQ, Enosawa S, Ogawa W, Inoue H, Okuyama T, Takeda K, Akira S, Ogino T, Irani K, Ozaki M.
Stat3 protects against Fas-induced liver injury by redox-dependent and -independent mechanisms. J. Clin.
Invest. 112: 989-998, 2003.
6.Iqbal M, Okazaki Y, Sharma SD, Okada S.
Nitroglycerin, a nitric oxide generator attenuates ferric nitrilotriacetate-induced renal oxidative stress, hyperproliferative response and necrosis in ddY mice. Biochim. Biophys. Acta 1623: 98-108, 2003.
7.Iqbal M, Sharma SD, Okazaki Y, Fujisawa M, Okada S.
Dietary supplementation of curcumin enhances antioxidant and phase II metabolizing enzymes in ddY male mice: possible role in protection against chemical carcinogenesis and toxicity.
Pharmacol Toxicol. 92: 33-38, 2003.
8.Iqbal M, Okazaki Y, Okada S.
In vitro curcumin modulates ferric nitrilotriacetate (Fe-NTA) and hydrogen peroxide (H2O2)-induced peroxidation of microsomal membrane lipids and DNA damage. Teratog Carcinog Mutagen. Suppl 1:151-160, 2003.
9.Fujisawa M, Notohara K, Tsukayama C, Mizuno R, Okada S.
CD56-positive cells with or without synaptophysin expression are recognized in the pancreatic duct epithelium: a study with adult and fetal tissues and specimens from chronic pancreatitis.
Acta Med Okayama. 57: 279-284, 2003.
10. Iqbal M, Okada S.
Induction of NAD(P)H:quinone reductase by probucol: a possible mechanism for protection against chemical carcinogenesis and toxicity.
Pharmacol Toxicol. 93: 259-263, 2003.
11. Hamazaki S, Okada S.
Expression of CD34 antigen in testicular mixed germ cell tumor. Pathol Int. 53: 853-857, 2003.
12. Iqbal M, Noor R, Mizuno R, Okada S.
Protective role of zinc-metallothionein (Zn-MT) in iron nitrilotriacetate (Fe-NTA)-induced renal oxidative damage.
Redox Rep. 8:163-167, 2003.
13. Hida AI, Kawabata T, Minamiyama Y, Mizote A, Okada S.
Saccharated colloidal iron enhances lipopolysaccharide-induced nitric oxide production in vivo.
Free Radic Biol Med. 34: 1426-1434, 2003.
14. Iqbal M, Sharma SD, Mizote A, Fujisawa M, Okada S.
Differential role of hydrogen peroxide and organic hydroperoxides in augmenting ferric nitrilotriacetate (Fe-NTA)-mediated DNA damage: implications for carcinogenesis.
Teratog Carcinog Mutagen. Suppl 1:13-21, 2003.
15. Okada S.
Prevention of free-radical mediated tissue damage and carcinogenesis induced by low-molecular-weight iron.
Biometals. 16:99-101, 2003.
16. 大森昌子、森下由美子、松岡博美、秋田みどり、大原信哉、濱崎周次
甲状腺内異所性胸腺の一例
日本臨床細胞学会岡山支部会誌 22: 19-20, 2003
17. 渡辺律子、松岡壮、大森昌子、豊田博
AFP産生卵巣漿液性乳頭腺癌の一例
日本臨床細胞学会岡山支部会誌 22: 29-30, 2003
ー総説・著書ー
1.Matsukawa A.
Regulation of innate immune response by Stat proteins during septic peritonitis. In: The biological response to planned and unplanned injuries: Cellular, molecular and genetic aspects.
Ogawa M, Yamamoto T, Hirota M,
ed. Excerpta Medica International Congress Series 1255, Elsevier, Amsterdam, Netherlnds, p7-14, 2003.
2.Chensue SW, Matsukawa A, Hogaboam CM, Kunkel SL.
Chemokines in granulomatous lung inflammation.
In: Chemokines in the lung. Strieter RM, Kunkl SL, Standiford TJ, ed. Marcel Dekker, New York, p221-238, 2003.
3.松川昭博炎症の分子機構（分担）
「図説分子病態学3版」一瀬白帝，鈴木宏治編、
PP. 83-88, 中外医学社、東京、2003
4.松川昭博：好中球と炎症（分担）
「Monthly Book Derma 75」
照井正、飯島正文、塩原哲夫編、PP. 1-7，全日本病院出版会、東京、2003
5.松川昭博：動物モデルにおける尿酸結晶誘発関節炎−サイトカイン・ケモカインの産生とそのネットワ−ク−（分担）
「高尿酸血症と痛風」11 : p147-151、メディカルレビュ−社、大阪、2003
ー国際学会発表ー
1.Ness T, Matsukawa A, Hogaboam CM, Kunkel SL. The immunoregulatory role of TARC in the innate immune response to sepsis. Experimental Biology 2003, April 11-15, 2003, San Diego, USA.
2.Hosako M, Ogino T, Omori M, Okada S. Cell cycle modulation by monochloramine and it’s mechanism. International Joint Meeting on Food Factors and Free Radicals in Health & Disease (FFFR2003). December 4-7, 2003, Kyoto, Japan.
２００２年業績
ー原著論文ー
1.Fujiwara K, Matsukawa A, Ohkawara S, Takagi K, and Yoshinaga M.
Functional distinction between CXC chemokines, interleukin-8 (IL-8), and growth related oncogene (GRO)-a in neutrophil infiltration.
Lab. Invest. 82: 15-23, 2002.
2.Matsukawa A, Lukacs NW, Hogaboam CM, Knibbs RN, Bullard DC, Kunkel SL, Stoolman LM.
Mice genetically lacking endothelial selectins are resistant to the lethality in septic peritonitis.
Exp. Mol. Pathol. 72: 68-76, 2002.
3.Namiki M, Kawashima S, Yamashita T, Ozaki M, Hirase T, Ishida T, Inoue N, Hirata K, Matsukawa A, Morishita R, Kaneda Y, Yokoyama M.
Local overexpression of monocyte chemoattractant protein-1 at vessel wall induces infiltration of macrophages and formation of atherosclerotic lesion: synergism with hypercholesterolemia.
Arterioscler. Thromb. Vasc. Biol. 22: 115-120, 2002.
4.Fujiwara K, Ohkawara S, Takagi K, Yoshinaga M, Matsukawa A.
Involvement of CXC chemokine growth-related oncogene-a in monosodium urate crystal-induced arthritis in rabbits. Lab.
Invest. 82: 1297-1304, 2002.
5.Montes R, Rodriguez-Wilhelmi P, Hurtado V, Matsukawa A, Montes M, Hermida J, Rocha E.
The endotoxin-induced plasminogen activator inhibitor-1 increase in rabbits is not tumor necrosis factor-a dependent and can occur in the absence of interleukin-1b. Thromb. Haemost. 88: 639-643, 2002.
6.Yoshida M, Nakamura T, Kikuchi T, Takagi K, Matsukawa A.
Expression of monocyte chemoattractant protein-1 in primary cultures of rabbit intervertebral disc cells. J.
Orthop. Res. 20: 1298-1304, 2002.
7.Rodriguez-Wilhelmi P, Montes R, Matsukawa A, Hurtado V, Montes M, Hermida J, Rocha E.
Interleukin (IL)-8 and growth related oncogene-a in severe endotoxemia and the effects of a tumor necrosis factor-a/IL-1b inhibitor on these chemokines.
Exp. Mol. Pathol. 73: 220-229, 2002.
8.Omori M, Ogino T, Than TA, Okada S.
Monochloramine inhibits the expression of E-selectin and intercellular adhesion molecule-1 induced by TNF-a through the supression of NF-kB activation in human endothelial cells.
Free Radical Res. 36: 845-852, 2002.
9.Mizote A, Hida AI, Hosako M, Fujisawa M, Kamekawa M, Okada S.
Effects of phlebotomy on the growth of ferric nitrilotriacetate-induced renal cell carcinoma.
Acta Medica Okayama 56: 199-204, 2002.
10. Minamiyama Y, Takemura S, Nishino Y, Okada S.
Organic nitrate tolerance is induced by degradation of some cytochrome P450 isoforms.
Redox Rep. 7: 339-342, 2002.
11. Hamazaki S, Ogino T, Tsukayama C, Okada S.
Expression of thyroid transcription factor-1 in strumal carcinoid and struma ovarii: an immunohistochemical study.
Pathol Int. 52:458-462, 2002.
12. 松岡壮，大森昌子，藤田勝，渡辺律子，豊田博
乳腺浸潤性多形性小葉癌の一例
日本臨床細胞学会岡山支部会誌 2１: 17-18，2002
13. 和仁洋治、飛田陽、津嘉山朝達
Gliosarcomaの1例
岡山外科病理雑誌 39：20-21，2002
ー総説・著書ー
1.Yoshinaga M, Ohkawara S, Matsukawa A.
Neutrophils as a cyokine-producing organ.
In: Helicobacter meets inflammatory bowel disease. Shimoyama T, Axon A, Lee A, Podolsky, DK, O'Morain C, ed. Medical Tribune Inc., Tokyo, Japan, p341-347, 2002.
2.ティンアウンタン、荻野哲也、大森昌子、寳迫睦美、川端晃幸、岡田茂
モノクロラミンによるエトポシド誘発性アポトーシスの抑制とDNA障害を持つ細胞の増加. 磁気共鳴と医学
12巻145-148, 2001
3.大森昌子、荻野哲也、Tin Aung Than、岡田茂
モノクロラミンによる、ヒト血管内皮細胞のTNF-alpha 誘発性細胞接着分子発現の抑制 磁気共鳴と医学、
13: 111-113，2002
ー国際学会発表ー
1.Matsukawa A, Takeda K, Kudo S, Maeda T, Akira S.
Mice with targeted disruption of Stat3 in macrophages and neutrophils are susceptible to septic peritonitis. Joint meeting of the International Society for Interferon and Cytokine Research,
The International Cytokine Society, The Society for Leukocyte Biology, and The European Cytokine Society, October 6-10, 2002, Turin, Italy.
２００1年業績
ー原著論文ー
ー原著論文ー
1.Matsukawa A, Kaplan MH, Hogaboam CM, Lukacs NW, Kunkel SL.
Pivotal role of signal transducer and activator of tanscription (Stat)4 and Stat6 in the innate immune response during sepsis.
J. Exp. Med. 193: 679-688, 2001.
2.Tateda K, Moore TA, Deng JC, Newstead MW, Zeng X, Matsukawa A, Swanson MS, Yamaguchi K, Standiford TJ.
Early recruitment of neutrophils determines subsequent T1/T2 host responses in a murine model of Legionella pneumophila pneumonia.
J. Immunol. 166: 3355-3361, 2001.
3.Tominaga K, Alstergren P, Kurita H, Matsukawa A, Fukuda J, Kopp S.
Interleukin-1b in antigen-induced arthritis of the rabbit temporo-mandibular joint. Arch Oral Biol 46:539-544, 2001.
4.Furue S, Mikawa K, Nishina K, Shiga M, Ueno M, Tomita Y, Kuwabara K,
Teshirogi I, Ono T, Hori Y, Matsukawa A, Yoshinaga M, Obara H.
Therapeutic time-window of a group IIA phospholipase A2 inhibitor in rabbit acute lung injury: correlation with lung surfactant protection.
Crit. Care Med. 29: 719-727, 2001.
5.Takahashi T, Suga M, Matsukawa A, Sato K, Okamoto T, Ichiyasu H, Ohkawara S, Yoshinaga M, Ando M.
Erythromycin attenuates an experimental model of chronic bronchiolitis via augmenting monocyte chemoattractant protein-1.
Eur. Respir. J. 17: 360-367, 2001.
6.Kuwabara K, Furue S, Tomita Y, Ueno M, Ono T, Matsukawa A, Yoshinaga M, Mikawa K, Nishina K, Shiga M, Obara H, Hori Y.
Effect of methylprednisolone on phospholipase A2 activity and lung surfactant degradation in acute lung injury in rabbits.
Eur .J. Pharmacol. 433: 209-216, 2001.
7.Than TA. Ogino T. Omori M. Okada S.
Monochloramine inhibits etoposide-induced apoptosis with an increase in DNA aberration.
Free Radical Biol. Med. 30: 932-940, 2001.
8.Uno M, Tsuchiyama J, Moriwaki A, Noguchi T, Mizoguchi K, Ogino T, Yoshino T, Okada S, Harada M.
In vitro induction of apoptosis for nasal angiocentric natural killer cell lymphoma-derived cell line, NK-YS,
by etoposide and cyclosporine A. Br. J. Haematol. 113: 1009-1014, 2001.
9.Hamazaki S, Nakashima H, Matsumoto K, Taguchi K, Okada S.
Metastasis of renal cell carcinoma to central nervous system hemangioblastoma in two patients with von Hippel-Lindau disease.
Pathol Int. 51: 948-953, 2001.
10. Hamazaki S, Yoshida M, Yao M, Nagashima Y, Taguchi K, Nakashima H, Okada S.
Mutation of von Hippel-Lindau tumor suppressor gene in a sporadic endolymphatic sac tumor. Hum.
Pathol. 32: 1272-1276, 2001.
11. Uno M, Tsuchiyama J, Moriwaki A, Noguchi T, Mizoguchi K, Ogino T, Yoshino T, Okada S, Harada M.
In vitro induction of apoptosis for nasal angiocentric natural killer cell lymphoma-derived cell line, NK-YS,
by etoposide and cyclosporine A. Br. J. Haematol. 113: 1009-1014, 2001.
12. Kakehashi C, Mori M, Kawabata T, Okada S.
In vitro transformation of rat renal cells by treatment with ferric nitrilotriacetate. Acta Med. Okayama. 55: 97-103, 2001.
13. Wani Y, Notohara K, Tsukayama C, Okada S.
Reduced expression of hMLH1 and hMSH2 gene products in high-grade hepatocellular carcinoma. Acta Med. Okayama. 55: 65-71, 2001.
14. 高橋利弘、菅守隆、佐藤圭創、岡本龍哉、一安秀範、松川昭博、大河原進、吉永秀、安藤正幸
緑膿菌誘発家兎びまん性汎細気管支炎におけるエリスロマイシンの効果-MCP-1産生増加による肉芽腫様病変の改善
Jpn. J. Antibiot（日本抗生物質学術協議会雑誌）54：125-129, 2001.
15. 藤田勝、松岡壮、渡辺律子、大森昌子、豊田博：外陰部
basaloid carcinoma の1例
日本臨床細胞学会岡山支部会誌 20: 34-35，2001
ー総説・著書ー
1.Matsukawa A, Lukacs NW, Hogaboam CM, Chensue SW, Kunkel SL. Chemokines and other mediators, 8. Chemokines and their receptors in cell-mediated immune responses in the lung. Microsc. Res. Tech. 53: 298-306, 2001.
ー国際学会発表ー
1.Matsukawa A,
Lukas NW, Hogaboam CM, Kunkel SL, Lira S. Resistance to septic peritonitis in mice lacking CC chemokine receptor 8 via augmenting innate immune response. Joint Meeting of Society for Leukocyte Biology and International Cytokine Society, November 8-11, 2001, Maui, HI, USA.
2.Rodriguez-Whilhelmi P, Montes R, Matsukawa A, Hurtado V, Montes M, Rocha E. The protective effect of FR167653, a simultaneous inhibitor of tumor necrosis factor-a and interleukin-1b, in rabbit sepsis is due to attenuation of the inflammatory response rather than to prevention of disseminated intravascular coagulation. Annual Meeting of the American Society of Hematology, December 7-11, 2001, Orlando, FL, USA.
3.Hida AI, Kawabata T, Minamiyama Y, Okada S. Iron preloading enhances Lipopolysaccharide(LPS)-induced nitric oxide(NO) and cytokine production in vivo. BioIron 2001, World Congress on Iron Metabolism, August 18-23, 2001, Cairns
Australia.